Platelet Rich Plasma (PRP) Specialist

Olayinka  Adepitan, MD -  - Interventional Pain Management

PainMD Associates

Olayinka Adepitan, MD

Interventional Pain Management & Ketamine Infusion Therapy located in Plano, TX

Dr. Olayinka Adepitan at Pain MD Associates in Plano, Texas, offers innovative and proven treatments to help enhance your healing, including cutting-edge platelet-rich plasma (PRP). These treatments are both excellent ways to help your body mend. Call Pain MD Associates or schedule a consultation with Dr. Adepitan online today to learn more.

Platelet Rich Plasma Q & A

What is Platelet Rich Plasma (PRP)?

Platelet Rich Plasma (PRP) is a biological means to stimulate wound healing and tissue regeneration by providing growth factors.

  • It is a volume of plasma that has a platelet count above that of whole blood.
  • The Platelet count in PRP is usually 4-8x that in whole blood.

Initially, PRP was used by orthopedists and sports medicine physicians to stimulate healing of athletic injuries - tendons, ligaments, muscles and bursae.

In recent years, pain physicians began to study and apply its use for treatment of chronic conditions.

PRP works through the many ‘Growth Factors’ it contains. These Platelet Derived Growth Factors function by:

  • Stimulating cells to divide and make copies of themselves
  • Promoting new blood vessels to form.
  • Promoting formation of new connective tissue for wound healing
  • Promoting the growth of structural and biochemical support for the cells.

Contained within the platelets, are 30+ bioactive proteins. Many of these are growth factors some of which are, ILGF-1, SDF1alpha, BMP, GDF-5, PDGF, TGF- beta1, VEGF, FGF, EGF.

PRP Indications

  • Tendinitis, Tendinopathy
  • Osteoarthritis or degenerative joint disease
  • Bursitis
  • Carpal tunnel syndrome, Cubital tunnel syndrome, Tarsal tunnel syndrome
  • Partial muscle tears, tendon tears and ligament tears
  • Degenerative Disc Disease
  • Lumbar Disc tears or rupture
  • Facet Syndrome
  • Sacro-iliac Joint Pain
  • Level 1 evidence for treatment of Elbow epicondylitis, Patellar tendinitis, Plantar Fascitis, Rotator cuff tear, Annular tear lumbar spine, Osteoarthritis knee. Level 2 for trochanteric bursitis.
  • PRP for elbow tendinitis (The American Journal of Sports Medicine Nov 2006 vol. 34 no. 11 1774-1778). Conclusions:
  1. Treatment of patients with chronic elbow tendinosis with PRP reduced pain significantly.
  2. PRP should be considered before surgery
  3. Further evaluation of this novel treatment is warranted


  1. 8 wks f/u: 60% improvement in VAS in PRP group vs. 16% with Bupivacaine.
  2. 6 months f/u: PRP group had 81% improved VAS.
  3. At mean 25.6 months f/u: PRP group had 93% improved VAS.


PRP  injections  are  used  to  treat  patients  who have  had  temporary  relief  from  steroid  injections  and  require  repeat  injections  on  a  regular  basis. Patients  with  various  tendon,  ligament  and  joint injuries  as  well  as  spine  pain. 

PRP Patient Instructions

  • Definitive results may take 3-6 months
  • Recommend stop NSAIDs for 7 days before and up to 2 weeks or more after Injection.
  • Avoid fluoroquinolones and statins if possible
  • Refrain from steroid injections into the treating joint for at least one month prior to procedure and do not administer at all after procedure. (Instead repeat PRP Injection)
  • Rest the joint for 1-6 weeks. Splinting of the joint may be required as directed by the physician.
  • Resume or start physical therapy as directed by the physician.
  • Re-evaluated after 6 weeks.